---
name: Clarenta
slug: comac-medical
site: cro
website_domain: clarenta.com
summary: Clarenta (formerly Comac Medical Group) is a pan-European CRO offering full-service trial delivery and early-phase studies, including first-in-human and PK work. It runs a Phase I unit in Sofia and has depth in oncology and rare diseases. Headquartered in Sofia, Bulgaria.
tagline: A new name for nearly three decades of clinical development experience
founded_year: 1997
employee_count_band: 201-1000
employee_count_label: 201–1,000
parent_name: 
parent_slug: 
hq_country: BG
tier2_domain_verified: false
updated_at: 2026-11-03T07:03:57.737Z
services_count: 8
modalities_count: 0
indications_count: 7
locations_count: 10
review_signal_gate: closed
generated_by: BioBM Editorial AI
---

# Clarenta

A new name for nearly three decades of clinical development experience

Listed on cro.directory.

## Summary

Clarenta (formerly Comac Medical Group) is a pan-European CRO offering full-service trial delivery and early-phase studies, including first-in-human and PK work. It runs a Phase I unit in Sofia and has depth in oncology and rare diseases. Headquartered in Sofia, Bulgaria.

## At a glance

- Founded: 1997
- Employees (est.): 201–1,000
- HQ country: BG

## Services

- Clinical Trial Services
- Phase I Clinical Trials
- Clinical Operations
- Regulatory Affairs
- Pharmacovigilance & Drug Safety
- Biostatistics & Statistical Programming
- Data Management & eClinical
- CMC Regulatory Submission Support

## Indications

- Oncology
- Rare Disease
- Neurology
- Psychiatry
- Respiratory
- Dermatology
- Gastroenterology

## Locations

- Sofia, Sofia, Bulgaria
- Paris, Paris, France
- London, London, United Kingdom
- Germany, Germany
- North Macedonia, North Macedonia
- Georgia, Georgia
- Poland, Poland
- Romania, Romania
- Turkey, Turkey
- United States (business development), United States

## Long description

## Overview

Clarenta, formerly Comac Medical Group, is a European clinical development partner. The organisation traces its origins to Comac Medical, established in Bulgaria in 1997 as a family-owned clinical research company, and rebranded as Clarenta on 9 September 2026. It has also expanded through the addition of Leads To Development (L2D) and ILIFE Consulting.

## Services

- **Clinical research consulting:** Advisory support on development pathways, risk assessment and programme decisions from scientific, clinical, regulatory and operational perspectives.
- **Full-service CRO:** Clinical operations, project management, regulatory affairs, medical oversight, data management, biostatistics and pharmacovigilance delivered as one accountable model.
- **Early phase development:** Early phase oncology trials, first-in-human studies, proof-of-concept studies and PK and clinical pharmacology studies.
- **Non-clinical and CMC:** Non-clinical development, CMC development and regulatory affairs, with L2D adding specialist non-clinical development, manufacturing and regulatory expertise.
- **Phase I Unit:** A dedicated unit in Sofia supporting studies in healthy volunteers and patients, with an on-site pharmacy and clinical laboratory.

## Therapeutic focus

The company reports depth in oncology and onco-haematology, rare diseases, neurology and psychiatry, respiratory diseases, dermatology and gastroenterology.

## Scale and footprint

Clarenta cites 29 years of clinical experience, more than 950 clinical trials, over 300 early-phase studies, over 150 oncology studies, and direct operational presence in 24 countries. Its largest team is in Bulgaria, with further teams in France, Germany, the United Kingdom, North Macedonia, Georgia, Poland, Romania and Turkey, and a business development presence in the United States. The company lists more than 300 colleagues.

## Positioning

Clarenta positions itself on clarity, transparent communication and senior expert access throughout a programme.

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_Profile last updated: 2026-11-03T07:03:57.737Z. Profile facts may include AI-assisted enrichment._

Auto-generated by BioBM Editorial AI for machine-readable profile access.