---
name: HitGen Inc.
slug: hitgen
site: both
website_domain: hitgen.com
summary: Provides DNA-encoded library (DEL) design and screening, FBDD/SBDD, medicinal chemistry, and oligonucleotide CDMO services. HAILO, its DEL+AI+Automation platform, supports molecular optimization for pharma clients. Headquartered in Chengdu, China.
tagline: DNA-encoded library discovery, FBDD/SBDD, and oligonucleotide CDMO services
founded_year: 
employee_count_band: 
employee_count_label: 
parent_name: 
parent_slug: 
hq_country: CN
tier2_domain_verified: false
updated_at: 2026-10-20T07:04:51.120Z
services_count: 9
modalities_count: 3
indications_count: 6
locations_count: 3
review_signal_gate: closed
generated_by: BioBM Editorial AI
---

# HitGen Inc.

DNA-encoded library discovery, FBDD/SBDD, and oligonucleotide CDMO services

Listed on cro.directory.

## Summary

Provides DNA-encoded library (DEL) design and screening, FBDD/SBDD, medicinal chemistry, and oligonucleotide CDMO services. HAILO, its DEL+AI+Automation platform, supports molecular optimization for pharma clients. Headquartered in Chengdu, China.

## At a glance

- HQ country: CN

## Services

- Discovery Research
- High-Throughput Screening
- Medicinal Chemistry
- Computational & In-Silico Drug Discovery
- Oligonucleotide Manufacturing
- Bioinformatics & Data Science
- Bioanalysis
- Analytical Method Development & Validation
- Preclinical In Vitro Studies

## Modalities

- Small Molecule
- Oligonucleotide
- Peptide

## Indications

- Oncology
- Immunology
- Ophthalmology
- Infectious Disease
- Metabolic
- Cardiovascular

## Locations

- Houston, Houston, United States
- Headquarters, Chengdu, China
- Cambridge, Cambridge, United Kingdom

## Long description

HitGen Inc. (SSE: 688222.SH) offers drug discovery services built around its DNA-encoded library (DEL) technology, which it has extended into fragment-based drug discovery (FBDD), structure-based drug design (SBDD), and related platforms.

**Services and capabilities**

- DEL design, synthesis, and screening, including DEL selection on targets such as PPIs, kinases, GPCRs, and RNA
- FBDD/SBDD, including off-rate screening and structure-based design
- Medicinal chemistry, synthetic and high-throughput chemistry, and analytical chemistry and quality research
- Oligonucleotide services, including nucleic acid sequence design, monomer and solid support chemistry, and oligonucleotide CDMO
- Biology support, including protein science, NGS and bioinformatics, cell biology, pre-clinical studies, and bioanalysis
- Computational chemistry and informatics

**Engagement models**

HitGen describes its business as technical services, project out-licensing, and product sales, and says it has worked with over 600 clients as of the end of 2025. Its services page describes comprehensive drug discovery support spanning hit identification, hit-to-lead, lead optimization, preclinical studies, and IND filing.

**Platforms and locations**

The company's HAILO platform combines DEL, AI, and automation for molecular optimization. HitGen is headquartered in Chengdu, China, and has subsidiaries in Cambridge, UK, and Houston, USA.

HitGen also advances internal programmes at clinical and preclinical stages.

## Related companies

- [Selvita](/companies/selvita) (Discovery Research, High-Throughput Screening) — [Compare](/compare/hitgen/selvita)
- [Synfini, Inc.](/companies/synfini) (Discovery Research, High-Throughput Screening) — [Compare](/compare/hitgen/synfini)
- [Taros Chemicals GmbH & Co. KG](/companies/tarosdiscovery) (Discovery Research, Medicinal Chemistry) — [Compare](/compare/hitgen/tarosdiscovery)
- [PozeSCAF Inc.](/companies/pozescaf-discovery-solutions) (Discovery Research, High-Throughput Screening) — [Compare](/compare/hitgen/pozescaf-discovery-solutions)
- [AAPharmaSyn](/companies/aapharmasyn) (Discovery Research, Medicinal Chemistry) — [Compare](/compare/aapharmasyn/hitgen)
- [Aurigene Pharmaceutical Services Limited](/companies/aurigeneservices) (Discovery Research, High-Throughput Screening) — [Compare](/compare/aurigeneservices/hitgen)
- [Vipergen](/companies/vipergen) (Discovery Research, High-Throughput Screening) — [Compare](/compare/hitgen/vipergen)
- [Axcelead Drug Discovery Partners, Inc.](/companies/axcelead) (Discovery Research, High-Throughput Screening) — [Compare](/compare/axcelead/hitgen)

_Profile last updated: 2026-10-20T07:04:51.120Z. Profile facts may include AI-assisted enrichment._

Auto-generated by BioBM Editorial AI for machine-readable profile access.