Simbec-Orion

Simbec-Orion is a contract research organisation with nearly five decades of experience delivering clinical trial management services. The organisation offers a comprehensive, full-service clinical development portfolio with the agility and structure to respond rapidly to client needs.

Core Services

• Clinical Trial Management: End-to-end clinical development solutions across all phases (Phase I through Phase IV and post-marketing)
• Clinical Pharmacology: First-in-human and Phase 1b/2a proof-of-concept studies, including PK, food effect, and drug-drug interaction studies at a purpose-built facility
• Central Laboratory Support: Routine safety testing, immunoassays, and bioanalytical laboratory services
• Biostatistics & Data Management: Biometrics team providing statistical analysis, planning, and reporting across all clinical phases
• IMP Management: Investigational medicinal product handling across all drug delivery routes

Therapeutic Expertise

Specialist experience in oncology, rare and orphan diseases, respiratory, dermatology, vaccines, and anti-infectives. The organisation positions itself as particularly passionate about rare diseases and oncology.

Operational Model

Structured to serve small and mid-size drug developers with tailor-made, scalable solutions. Global team with centralised leadership and international reach. Approximately 90% of clinical pharmacology work involves Investigational Medicinal Products.