Swiss BioQuant AG

Bioanalysis for small and large molecules

Swiss BioQuant describes itself as a bioanalytical contract research organization focused on LC-MS/MS and ligand-binding assays. Services cover method development, validation, and sample analysis for both small and large molecules in non-clinical and clinical studies.

• LC-MS/MS: High-performance liquid chromatography coupled with tandem mass spectrometry for quantitative analysis in complex biological matrices.
• Ligand-binding assays: Used for proteins, peptides, and antibodies in pharmacokinetic (PK) and pharmacodynamic (PD) studies.
• Biomarker and metabolite determination: Drug, metabolite, and biomarker determination in preclinical and clinical studies.
• Cell and gene therapy bioanalysis: qPCR for nucleic acid quantification, including vector copy number and gene expression.

Quality and compliance

The company states that its work is performed in a 21 CFR Part 11 compliant environment. It also reports a validated electronic archiving system and an automated data evaluation and reporting system. Its test facility has been inspected by Swissmedic since 2008, and the excerpts describe GLP compliance under the Swiss Ordinance relating to Good Laboratory Practice.

Experience

The company cites more than 20 years of LC-MS/MS and ELISA bioanalysis experience, with work supporting new drug entities and generics applications.