Synfini, Inc.

Overview

Synfini provides an Agile Chemistry Foundry platform for accelerated drug discovery, integrating AI-driven molecular design with automated synthesis and testing capabilities. The platform combines an open-architecture, cloud-based dry lab with robotic wet lab automation to streamline DMTA (design-make-test-analyze) cycles.

Core Capabilities

Discovery Workflows & Planning

• Organized workflows, data, and analysis for efficient discovery programs
• Target-to-preclinical candidate solutions
• Lead optimization and hit discovery support

AI-Driven Design & Optimization

• Generative design with integrated AI molecular design and synthetic planning
• Custom target-specific models and advanced ADME/Tox models
• Multi-parameter optimization for all stages of discovery
• Synthetically accessible hit and lead generation

Automated Synthesis & Testing

• Flexible robotic wet lab for high-throughput experimentation (HTE)
• SynBuild™ automated synthesis suite with integrated microscale purification
• Rapid compound isolation and purification at microgram to low-milligram quantities
• Move from synthesis to biological testing in hours

Chemistry Expertise

• Broad chemistry expertise across the majority of chemical modalities
• Support for diverse targets and therapeutic indications
• Proprietary chemistry data and extensive reaction catalog

Deployment Model

Synfini offers cloud-based access to advanced AI and robotic laboratory automation without the cost of building in-house infrastructure. The platform is open and configurable, integrating seamlessly with existing tools, data, and workflows. The flagship Foundry is expandable to new locations globally or deployable on-premise.