Champions Oncology

Overview

Champions Oncology is a leading preclinical and clinical oncology CRO, dedicated to accelerating drug development through innovative research solutions and clinically relevant tumor models.

Key Capabilities

Preclinical Platforms:

• Over 1,400 patient-derived xenograft (PDX) models and primary hematological models with comprehensive multi-omic characterization
• Proprietary Lumin bioinformatics platform integrating WES, RNA-seq, proteomics, cell surface, and functional data
• Custom in vivo and ex vivo testing platforms
• Radiopharmaceutical development and testing in clinically relevant PDX models

Analytical & Molecular Services:

• Next Generation Sequencing (WES, RNA-seq) for biomarker discovery and gene expression analysis
• Label-free DIA 4D quantitative proteomics and phospho-proteomic analysis
• Western blotting protein detection assays
• GCLP High Complexity Flow Cytometry
• Histology and immunohistochemistry (IHC) with automated technology
• Target and biomarker validation

Clinical Services:

• Clinical specialty testing and FIH (First-in-Human) trial support
• Custom flow cytometry development for clinical programs

Differentiation

Champions combines the most comprehensive PDX platform in oncology with a proprietary multi-omics data ecosystem containing over 2 billion data points, supporting programs from target identification through biomarker discovery and clinical translation. The Lumin platform provides real-time insights into tumor genetics and therapeutic responses, enabling data-driven decision-making across development timelines.