SGVector

Overview

SGVector is a viral vector development and manufacturing partner specializing in advancing cell and gene therapies globally. The company operates a scalable, suspension-based viral vector production platform designed to meet regulatory requirements for safety, purity, and quality.

Core Services

Vector Design & Development

• Design and development of functional viral vectors
• Design of Rep-Cap helper and transfer plasmids
• Optimization of transgene expression to enhance vector functionality for research and clinical applications

Process Development, Scale-Up & Production

• Process optimization from small scale to large-scale manufacturing
• Cell expansion, transfection, clarification, purification, polishing, formulation, and filling
• Full production and manufacturing support

Assay Development & Analytical Testing

• Assay development and testing to ensure quality, purity, and potency of viral vector products
• Safety testing and analytical characterization

Facility & Infrastructure

SGVector operates a 250-square-meter facility at Ngee Ann Polytechnic in Singapore, equipped with modern equipment including bioreactors up to 50L, chromatography systems, TFF systems, dPCR and qPCR systems, and warehousing for raw materials, plasmids, master cell banks, and finished products.

Focus Areas

The company emphasizes process optimization and cost reduction during development and production of viral vectors. With over 200 FDA-approved clinical trials involving AAVs and rapid development of AAV-based gene therapies, SGVector addresses the urgent need for scalable manufacturing platforms to meet increasing demand for recombinant AAVs.