JOINN Biomere

JOINN Biomere is a preclinical contract research organization (CRO) located in Worcester, MA, in the greater Boston area. The organization specializes in non-GLP PK/PD and early toxicology studies across small and large animal models, including non-human primates.

Core Capabilities

• PK/PD Studies: Comprehensive pharmacokinetics and pharmacodynamics evaluation in rodent and large animal models
• Early Toxicology: Non-GLP early tox studies to support go/no-go decision-making
• ADME Studies: Absorption, distribution, metabolism, and excretion evaluation
• Disease Models: Ocular disease models, CNS dosing, metabolic disease models, and preclinical oncology models
• Endpoint Analysis: Fully equipped labs with multidisciplinary scientific support
• Gene Therapy PK/PD: Specialized services for gene therapy candidates
• Organ-Chip Services: Advanced in vitro-to-in vivo translation capabilities
• Colony Management & Surgical Services: Dedicated animal model support

Regulatory Status & Accreditations

Biomere is AAALAC accredited, OLAW Assured, DEA Licensed, and USDA Registered. The organization operates with extensive vivarium capacity and fully equipped laboratories.

Global Reach

Acquired by JOINN Laboratories (China) in 2019, Biomere now offers access to a global preclinical network. JOINN Laboratories operates facilities in Suzhou, Beijing, Wuzhou, Chongqing, and Guangzhou in China, and maintains a vivarium in Richmond, CA. This combination enables clients to leverage both non-GLP and GLP study capabilities, with options to reduce time and cost by placing GLP-toxicology programs in China.

Scientific Approach

Biomere emphasizes a personal approach combining scientific expertise with dedicated project resourcing, model availability, and expedited start times. The organization focuses on generating PK/PD and early tox data to support the lead optimization to IND-enabling transition, evaluating various small molecules and complex biologics across different disease states.