Cyagen Biosciences

Overview

Cyagen Biosciences is a preclinical CRO specializing in genetically engineered animal models, custom cell line development, and viral vector packaging for drug discovery and development.

Core Services

Genetically Engineered Animals

• Knockout, knockin, and transgenic mice and rats with high genetic precision
• Humanized target gene models (HUGO-GT™ platform)
• Disease-specific models spanning neurology, ophthalmology, oncology, metabolic/cardiovascular, and autoimmune indications
• Breeding, cryopreservation, recovery, and phenotyping services

Custom Cell Lines

• Induced pluripotent stem cells (iPSCs)
• Knockout and knockin cell lines
• Point mutation and overexpression cell lines
• Tumor and knockout cell line product catalogs

Viral Packaging & Gene Therapy Support

• Adeno-associated virus (AAV) packaging with AI-powered discovery
• Lentivirus and adenovirus packaging
• Support for gene therapy and vaccine R&D applications

Antibody Therapy CRO Services

• Fully human antibody mice (HUGO-Ab™ platform)
• AI-powered screening for candidate selection
• Discovery-to-validation support

Preclinical Efficacy Studies

• Neuroscience models (Alzheimer's, Parkinson's, Huntington's, blood-brain barrier)
• Ophthalmology models (glaucoma, age-related macular degeneration)
• Oncology and immuno-oncology models
• Metabolic disease and anti-obesity models
• Autoimmune and inflammatory disease models

Facilities & Quality

Cyagen operates AAALAC-accredited facilities housing 250,000 SPF animals, upholding high standards in animal welfare and research quality. The organization has delivered over 50,000 mouse and rat models globally and maintains 16,500+ SCI journal citations.

Market Position

With 20 years of genetic innovation and 10,700 global bioscience partners, Cyagen positions itself as a technology-driven partner bridging preclinical research and IND applications through integrated model development and expert-led studies.