CROs offering Preclinical In Vitro Studies with Small Molecule

Matching companies

• Allucent

  Allucent is a full-service CRO specializing in clinical development solutions for small and mid-sized biotech companies.

• Altasciences

  Mid-size early phase CRO/CDMO in Canada and the U.S. offering preclinical safety testing, clinical pharmacology (Phase I–II), bioanalysis, research services, and manufacturing with integrated capabilities.

• Aragen Life Sciences

  Global CRDMO partner offering integrated discovery-to-commercialization services across small molecules and biologics, with 4000+ scientists and R&D/manufacturing campuses in Asia, North America, and Europe.

• Axcelead Drug Discovery Partners, Inc.

  Axcelead provides integrated drug discovery research services to pharmaceutical companies, biotech ventures, and academic institutions. Founded in 2017 from Takeda's drug discovery research base, the company offers expertise across small molecules, nucleic acids, antibodies, and multiple therapeutic modalities.

• BioDuro-Sundia

  BioDuro-Sundia is a contract research, development, and manufacturing organization (CRDMO) with 30 years of expertise providing integrated drug discovery, development, and manufacturing services from target identification through IND submission.

• Biotest Facility

  Danish CRO offering in vivo models, proteomics, transcriptomics, biomarker discovery, and bioinformatics to support biotech and pharma research from concept to validated data.

• Cardiomedex

  Cardiomedex is a preclinical CRO specialized in cardiovascular disease models, offering in vivo efficacy studies, ex vivo functional exploration, and in vitro assays for drug candidates targeting heart failure, myocardial infarction, hypertension, and cardiometabolic complications.

• Certara

  Certara transforms drug development with proprietary biosimulation software, predictive modeling, and AI-driven services spanning discovery through commercialization. Serving 2,400+ biopharmaceutical companies and regulatory agencies across 70 countries, Certara's model-informed drug development (MIDD) platform accelerates clinical and regulatory decision-making.

• Champions Oncology

  Leading oncology CRO specializing in preclinical and clinical specialty testing, with over 1,400 patient-derived xenograft models, comprehensive multi-omic datasets, and proprietary platforms including flow cytometry, NGS, proteomics, and histopathology services.

• ChemDiv

  ChemDiv is a fully integrated target-to-clinic CRO headquartered in San Diego, CA, offering drug discovery services including medicinal chemistry, CADD, ADME/DMPK, toxicology, and custom synthesis alongside the industry's largest commercial screening library of 1.6M compounds.

• ChemPartner

  Global preclinical CRO with 20+ years of experience supporting drug discovery through IND submission across small molecules and biologics, with 2,000+ scientists and facilities worldwide.

• Creative Bioarray

  Creative Bioarray provides preclinical research solutions including drug screening, ADME-PK, toxicity studies, and cell-based services across oncology, neurology, cardiovascular, and metabolic therapeutic areas.

• Crown Bioscience

  Preclinical oncology CRO offering 2,500+ PDX models, organoid and cell line databases, and translational platforms with biomarker discovery and AI-driven systems biology for drug development.

• Evotec

  Evotec is a life science company pioneering drug discovery and preclinical development. The organization leverages cutting-edge technology, disruptive science, and extensive disease knowledge to accelerate the journey from concept to cure.

• Frontage Laboratories

  Global pharmaceutical development organization offering integrated drug discovery, preclinical safety/toxicology, DMPK, bioanalytical, and clinical trial services across 28 sites with 2,200 employees and 200+ FDA inspections.

• HitGen Inc.

  Provides DNA-encoded library (DEL) design and screening, FBDD/SBDD, medicinal chemistry, and oligonucleotide CDMO services. HAILO, its DEL+AI+Automation platform, supports molecular optimization for pharma clients.

• ITR Laboratories

  GLP-compliant nonclinical CRO specializing in safety and toxicology testing across in silico, in vitro, and in vivo modalities, with 35+ years of experience and nearly 6,000 completed studies.

• Labcorp

  Labcorp is a global life sciences and healthcare company providing diagnostic testing, drug development, nonclinical research, central laboratory services, and real-world data solutions to healthcare providers, health systems, and biopharma companies.

• Medpace

  Full-service CRO with 30+ years of organic growth, offering integrated clinical development services across all phases with wholly-owned central labs, bioanalytical lab, imaging core lab, and Phase I unit.

• Noble Life Sciences

  Advanced preclinical CRO providing comprehensive drug and device development services including bioanalysis, GLP toxicology, pharmacodynamic modeling, and specialized testing for oncology, infectious disease, gene therapy, and synthetic biology programs.

• Nuvisan

  Full-service CRO and CDMO with specialized competency centers in drug discovery, formulation development, GMP manufacturing, and bioanalytical services across Germany and France.

• Oncodesign Services

  Contract research organization specializing in drug discovery and preclinical services for oncology, inflammation, and infectious diseases since 1995.

• PI Health Sciences

  PI Health Sciences is an integrated CRDMO offering end-to-end drug discovery, development, and manufacturing services with R&D and manufacturing locations in Europe and India.

• Pharmaron

  Premier life science CRO and CDMO offering integrated R&D and manufacturing across drug discovery, preclinical, clinical development, and commercialization for small molecules, biologics, and cell & gene therapies. 25,000+ employees across China, US, and UK.

• Premier Research

  Premier Research is a global full-service CRO delivering clinical research and development solutions across the complete drug development lifecycle. The organization provides comprehensive capabilities spanning study design, study startup, medical affairs, biostatistics and data management, central monitoring, clinical monitoring and site management, project and risk management, safety and pharmacovigilance, quality and compliance, and medical writing.

• Proone Labs

  Proone Labs provides preclinical pharmacology, drug discovery, and regulatory support services to biotech startups, traditional pharma, and in-silico companies. The team has delivered 30+ assays, 50+ cell lines, and supported 4 FDA drug approvals across multiple therapeutic areas.

• Protheragen

  Specialized preclinical CRO dedicated to obesity research, offering comprehensive animal models, pharmacokinetic/pharmacodynamic studies, bioanalysis, and safety assessment for anti-obesity drug development.

• QPS

  QPS provides integrated contract research and clinical services spanning bioanalysis, preclinical development, and early-to-late phase clinical trials across multiple therapeutic areas including oncology, dermatology, and women's health.

• Reaction Biology

  Global preclinical CRO specializing in kinase drug discovery, cell-based assays, in vivo pharmacology, and immuno-oncology with 1,000+ cell lines and hundreds of validated protein targets across US and EU facilities.

• ReechPharma, LLC

  ReechPharma specializes in customized formulation development and drug delivery systems for preclinical and clinical stages, supporting biotech and pharma companies with formulation research, analytical services, and GMP manufacturing.

• Selvita

  Selvita is an integrated drug discovery and development service provider offering comprehensive solutions from target validation through preclinical candidate nomination and clinical manufacturing, with expertise in small molecules, antibodies, and protein degraders.

• Syngene International

  Innovation-led CRDMO offering integrated scientific services from early discovery through commercial manufacturing, with cGMP-compliant facilities, 5,200+ scientists, and a new 50,000-liter single-use bioreactor capacity in the U.S.

• Tigermed

  Leading global CRO providing end-to-end clinical trial services, preclinical development, medical device and IVD trials, regulatory affairs, and real-world evidence studies across 180+ offices serving 4,000+ customers.

• WuXi AppTec

  Global CRDMO platform providing integrated end-to-end contract research, development, and manufacturing services across discovery, preclinical, clinical, and commercial phases for small molecules, peptides, oligonucleotides, and biologics across 30+ countries.